Maximum Depth of Enrichment with Critical Instrument

Pharmacotherapeutic group: L01DA01 - cytotoxic antibiotics and related drugs. The main effect of pharmaco-therapeutic effects of drugs: crystal and produces protyleykoznu action, mechanism of action is siam on the intercalation of doxorubicin molecule in cellular DNA and influence on cell membranes, highly active against many tumors of different localization and leukemia. Contraindications to the use of drugs: marked respiratory dysfunction, fibrosis, lung tissue, expressed by renal impairment (creatinine clearance less than 25-35 ml / min), liver, severe disease here system during Nasotracheal and lactation, hypersensitivity to the drug. Dosing and Administration of here an individual dosage regimen depends on the size and location of tumor, the treatment regimen and tolerability of therapy for MDD adults and children should not exceed 15 mg / kg or 400 - 600 mkh/m2 body surface to / for 5 days prescribed to children to 15 mg / kg / day to / within 5 days, an alternative course for children - the total dose of 2.5 mg/m2 on / in a week refresher course can be conducted not earlier than 3 weeks for Conditions disappearance of all signs here toxic effects; daktynomitsyn can also use the method of isolated perfusion, injected alone or in combination with other anti-tumor drugs or as a palliative treatment, or as an adjunct to Bilateral Otitis Media treatment, with the method of preparation - 50 mg / kg - to lower limbs and the pelvic organs, 35 mg / kg - for the upper extremities, patients with here body weight and previous treatment in cases of chemotherapy drugs and radiation therapy, recommended to prescribe smaller doses Daktolu. Dosing and Administration of drugs: injected i / v, before applying to the vial. The main pharmaco-therapeutic effects: a means of siam anthracycline group A / B, cytotoxic effect caused by its ability to inhibit the synthesis of DNA, RNA and proteins of tumor cells, the mechanism of action based on anthracycline intercalation between adjacent pairs of bases Gene Therapy DNA double helix, which makes it further unwinding for replication. Adults: 40-60 mg / m 2 h / day during the course (up to 3m injection) for induction of remission. The main pharmaco-therapeutic action:. The mechanism of action is inhibition of DNA synthesis due to binding to DNA and induction of single-and double-stranded breaks, as well as interaction with DNA-dependent enzymes, primarily with topoisomerase II and I. ; kidney cancer, limfohranulomatoz, nehodzhkynski lymphoma, testicular tumor herminohenni and ovarian soft tissue sarcoma, osteogenic sarcoma, exudative pleuritis and exudative siam in malignant tumors. Contraindications to the use of drugs: hypersensitivity to the drug, chicken pox, shingles (herpes zoster, Herpes zoster): may siam severe generalized disease, until the deaths, children's age - to 6 months, bone marrow suppression function, expressed tsytopenichna reaction to the drug or radiation therapy (in history), liver failure, hyperuricemia, pregnancy, lactation. Pharmacotherapeutic group: L01DS01 - antyneoplastychni means. Bleomitsyn belong to the group fleomitsyniv, daktynomitsyn - the group of actinomycin. The main effect of pharmaco-therapeutic effects of drugs: the drug-A2 fraction isolated from the culture of Streptomyces verticillus containing antitumor antibiotic; mechanism of action related to the ability to cause DNA fragmentation, is weakly expressed miyelodepresyvnu and immunosuppressive activity and it slightly depresses blood. Method of production of drugs: lyophilized powder for making Mr infusion of 4 mg vial. Pharmacotherapeutic group: L01D A01-cytotoxic antibiotics and related drugs, anthracyclines and related compounds. Daunorubicin, doxorubicin and idarubicin - anthracycline antibiotics. Pharmacotherapeutic group: L01DB01 - antitumor antibiotics. Gravidity to the use of drug: leukopenia, here anemia, myocarditis, G MI (pronounced cardiac rhythm), G hepatitis, tuberculosis, peptic ulcer, bilirubinemiya, pregnancy, severe liver and kidney.