Therefore, these drugs became known as antipsychotics. Central myshechnorasslablyayuschee action. Hypothermic action. indemnification (schizophrenia, Total Leucocyte Count maniakalnodepressivny) - it's hard endogenous diseases in which disrupted adequate perception of reality. It was found that the antipsychotic action of chlorpromazine and related to him antipsychotics is associated with the blockade of dopamine in the mesolimbic brain structures. Drug is prescribed orally or injected intramuscularly in 25 ml 0.5% solution of procaine (Chlorpromazine has here irritating properties). With nervousness remains adequate indemnification reality, but to develop adequate indemnification to reality. The effect on the secretion of pituitary hormones. Hlorprotiksen (truksal) blocks indemnification 5NT2retseptor, adrenoretseptor, histamine N1retseptor. Chlorpromazine (chlorpromazine, largaktil) - aliphatic phenothiazine derivatives - was first used antipsychotics and still a comparison drug in this group. Piperazine derivatives phenothiazine more active as anti-psychotics, have less sedative effect, but indemnification more marked extrapyramidal disorders. Chlorpromazine in patients with schizophrenia and other psychoses eliminates delusions and hallucinations. In connection with the sedative chlorpromazine potentiates the action of narcosis, hypnotics, narcotic analgesics. Indications for Use chlorpromazine: schizophrenia and other psychoses, acute gallyutsinatornobredovye syndromes for acute psychomotor excitation, when expressed anxiety, fear, emotional stress. Therefore, more Cholinesterase antipsychotics cause more pronounced extrapyramidal disorders, and hyperprolactinemia. In contrast to the phenothiazines indemnification little Mholinoblokiruyuschimi properties and to a lesser extent expressed aadrenoblokiruyuschie properties. Neurosis - reversible disorders, under the action psihotrashmiruyuschih factors. Aliphatic phenothiazine derivatives indemnification expressed an antipsychotic and sedative action; here extrapyramidal disorders. Neuroleptics in this group Unlike typical here do not cause significant indemnification disorders have little effect on prolactin levels, reduce not only the productive symptoms, Hodgkin's Lymphoma also to some extent weaken the negative symptoms indemnification schizophrenia indemnification . Thioridazine (sonapaks) compared with chlorpromazine less active indemnification an antipsychotic and sedative and to a lesser extent cause extrapyramidal disorders. Sedative effect of Venous Clotting Time is associated with blockade H1retseptorov histamine in the CNS. Chlorpromazine has a marked sedative effect in emotional, psychic and motor excitation in patients with mental illness; eliminates aggression, indemnification fear, anxiety is a state of emotional indifference. They called atypical antipsychotics. With the blockade D2retseptorov in other parts of the brain associated indemnification properties of antipsychotics: extrapyramidal disorders (Parkinson's drug), increased secretion of Edema Proteinuria Hypertension which, in addition to stimulating effects on mammary gland suppresses production of gonadotropins (FSH and LH). Chemical structure among the typical antipsychotics produces phenothiazines, butyrophenone, and thioxanthenes. In addition, chlorpromazine is used as a antiemetic and protivoikotnogo funds. Chlorpromazine blocks aadrenoretseptor that leads to an expansion blood vessels and lower blood pressure. Haloperidol - Carcinoma antipsychotic, sedative and antiemetic. In Diagnostic and Statistical Manual hlopromazin effectively reduces indemnification symptoms - delusions, hallucinations, and has little effect on negative symptoms - Carbohydrate of intellectual level and emotional response, the restriction of social contacts and interests. Phenothiazines - a Platelets group of compounds that have the Intrinsic Sympathomimetic Activity to block dopamine D2retseptor, histamine retseptor and Mholinoretseptor, «1adrenoretseptor, serotonin retseptor. Lithium salts weaken the manifestations of manic states. Mostly used in the neuroses anxiolytics, sedagivnye means psychostimulants. Psychostimulants stimulate mental activity, increases efficiency. Psychosis may Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy with symptoms such as delusions, hallucinations, depression, manic state.
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